The APUA Newsletter has been published quarterly since 1982. The Newsletter contains expert information on antibiotic use and resistance for healthcare practitioners, researchers and policy makers. It is distributed to several thousand individuals, including our members, organizations and libraries worldwide.

To receive the latest issue of the APUA Newsletter, please email

To contribute to the APUA Newsletter, see the Instructions for Authors.


2009 Vol 27 No 1 & 2        How harmless bacteria turn harmful: Mobile DNA and the recruitment of virulence factors

2009 Vol 27 No 3              Drug resistance challenges of the flu pandemic


2008 Vol 26 No 1              New Data and Resources Advance Study of Reservoirs of Resistance (ROAR)

2008 Vol 26 No 2&3         Infection Control: A Potent Antimicrobial Resistance Containment Strategy


2007 Vol 25 No 1              Better Diagnostics - A Means for Selecting More Effective Antimicrobial Agents

2007 Vol 25 No 2             Extended Spectrum Beta-Lactamases: An Escalating Concern

2007 Vol 25 No 3             Treating Enteric Infections in the Developing World


2006 Vol 24 No 1              Antibiotic Stewardship Programs: Proven Strategies to Preserve Medicine's 'Magic Bullets'

2006 Vol 24 No 2             Biopreparedness: A Path to Infectious Disease Control

2006 Vol 24 No 3             Acute Respiratory Infections in Resource-Poor Countries


2005 Vol 23 No 2             ROAR: A Focus on Reservoirs of Antibiotic Resistance

2005 Vol 23 No 1              APUA Tackles the Global HIV/AIDS epidemic


2004 Vol 22 No 3             Focus: Emerging Antimicrobial Resistance Threats: Gram-negatives, AMR Bioweapons, HIV, Malaria, and TB

2004 Vol 22 No 2             Focus: Antimicrobial Use in Agriculture: How Risky?

2004 Vol 22 No 1              Focus: AMR Model Interventions Under the Microscope


2003 Vol 21 No 4              Focus: The AMR Threat in AIDS, TB, Malaria

2003 Vol 21 No 3              Focus: Antibiotic Resistance in the Developing World

2003 Vol 21 No 2              Focus: MRSA in the Community (CMRSA)

2003 Vol 21 No 1               Focus: Uncomplicated Urinary Tract Infections


2002 Vol 20 No 4             Focus: Antimicrobial Resistance in Africa

2002 Vol 20 No 3             July Report of Fully Resistant VRSA: A Major New Health Threat - One on One with J. Glenn Morris, Jr., MD 

                                          Alternatives to Vancomycin Use for MRSA 

2002 Vol 20 No 1              A New Strategy for Fighting Vancomycin-Resistant Enterococci (figure 3)

                                          Probiotics: Using Live Microbes to Decrease Antimicrobial Use

                                          Quinolone Resistance in Vietnam

                                          … also APUA's ROAR program, early warning by GAARD, APUA's 20th anniversary, APUA chapter news


2001 Vol 19 No 4              Antibiotic Resistance in Long-Term Care

                                         Making Official Use and Dosage Recommendations for Generic Antibiotics in Belgium

                                         … also US Federal Action Plan on Antibiotic Resistance, Bioterrorism and Antibiotics, APUA chapter news

2001 Vol 19 No 3               Looking Back on Two Decades: 20th Anniversary of APUA

                                          The Future of the Quinolones

                                          Antibiotics with a Chaser of Bacteria? Recololonization with commensal bacteria reduces recurrences of acute otitis media and pharyngotonsillitis

                                          Ask the Expert: Are antibiotics always needed immediately for acute otitis media?

                                          … also GAARD: global surveillance; research from APUA chapters

2001 Vol 19 No 2               Infection Control in Healthcare Facilities

                                          Guidelines for Antibiotic Use from the American College of Physicians

                                          Chile Enforces Regulations on the Sale and Dispensing of Antibiotics

                                          … also environmental impact of antibiotics; Guadalajara Declaration

2001 Vol 19 No 1                Antibiotic Use and Resistance: What Lies Beneath!

                                          Photobactericides-"Lightening" the Antibiotic Load

                                          … also fluoroquinolones & poultry; APUA survey of physicians


2000 Vol 18 No 4             Neisseria gonorrhoeae Drug Susceptibility in Buenos Aires, Argentina

                                         The HARMONY Project's Antibiotic Policy and Prescribing Process Tool

                                         … also antibiotics and food animals; public policy notes

2000 Vol 18 No 3            Method of Physician Remuneration and Its Impact on Antibiotic Prescription Rates

                                        Formula to Help Select Rational Antimicrobial Therapy: A Comparison for Community-Acquired Pneumonia

                                        Ask the Expert: What is appropriate empiric therapy for active tuberculosis?

                                        … also APUA Chapter meetings; GAARD formation announced

2000 Vol 18 No 2            Nasopharyngeal Carriage of Penicillin-Resistant S. pneumoniae in Daycare Centers in Sofia, Bulgaria

                                        Antibiotics in Aquaculture: Questionable Risk to Public Health

                                        Editorial: The Role of Surveillance

                                        … also APUA's small grants program; FAAIR project; Infectious Disease Congress in Argentina

2000 Vol 18 No 1            Antibiotic Use in Food-Animal Production in Denmark

                                       Antimicrobial Agents in Aquaculture: Potential Impact on Public Health

                                       Ask the Expert: What are the criteria for diagnosing sinusitis in children? How can one differentiate it from a simple cold with mucopurulent rhinitis?

                                       … also APUA-Moldova holds week-long training; CME courses; surveillance and drug policy in Italy


1999 Vol 17 No 4             The Emergence and Spread of Antibiotic Resistance in Food-Borne Bacteria in the United Kingdom

                                        The Maintenance of Resistance

                                        Antibiotic Prescribing in Pakistan

                                        … also ROAR network; Spanish language list-serve

1999 Vol 17 No 3             Silver cations as an antimicrobial agent: clinical uses and bacterial resistance.  Silver S, Lo J-F, Gupta A

                                        Antibiotic usage in dermatology.  Feingold DS

                                        Community-acquired bacterial pathogens in Singapore: changes and challenges.  Ling M-L

1999 Vol 17 No 2             The mar regulon specifies an intrinsic bacterial response to antibiotics.  Alekshun MN

                                        Appraisal of the current recommendations for antibiotic prophylaxis of infective endocarditis.  Brusch JL

1999 Vol 17 No 1              Antimicrobial resistance in Lebanon.  Araj GF

                                       Antibiotic use in plant disease control.  McManus PS

                                       Ask the expert: Is amoxicillin still appropriate for the treatment of infections caused by non-susceptible isolates?  Low DE  …(Spanish version)


1998 Vol 16 No 4             Macrolide resistance in Streptococcus pyogenes in Europe.  Cornaglia G, Huovinen P

                                        Effect and economic impact of a "Standardized Orders for Antimicrobial Prophylaxis" program.  Frighetto L et al

                                        Ukrainian version 

1998 Vol 16 No 3             Antimicrobial use and antimicrobial resistance among healthy children in Bolivia.  Bartoloni A

                                        Antibiotic use in animal husbandry and resistance development in human infections.  Witte W

1998 Vol 16 No 2             Antimicrobial resistance of H. pylori in Poland.  Rozynek E et al

                                        Preventative methods replace antibiotic growth promoters: ten years experience from Sweden.  Wierup M

1998 Vol 16 No 1              The spread of macrolide-resistant streptococci in Italy.  Cornaglia G

                                        Towards coordinated surveillance of antimicrobial resistance: the need to merge surveillance databases.  O'Brien TF

                                        Surveillance systems around the world.  APUA

                                        Letter to the editor: In vitro studies are not dogma.  Amsden GW


1997 Vol 15 No 4              Antibiotic prescribing, controls and antimicrobial resistance: an Australian experience.  Baird RW

                                         Bacterial conjunctivitis: diagnosis and treatment …(Russian translation, see page 1)  Baum JL

1997 Vol 15 No 3              Examining vancomycin use in hospitalized Medicare patients in the United States.  Peto RR

                                         Antibiotic resistance in two university hospitals in Sofia, Bulgaria  Keuleyan EE, Haralambieva YH, Gergova RP, et al.

1997 Vol 15 No 2              Mechanisms of antibiotic resistance in oral bacteria.  Roberts MC

                                         Parents' impact on antibiotic use.  Bauchner H

1997 Vol 15 No 1               Trends in antibiotic resistance associated with E. coli calf scours.  White DG, Moen M, Huber D

                                         Antibiotics in dentistry--a boon or bane?  Walton RE, Zerr M, Peterson L

                                         Ask the expert: Are urine cultures always necessary before initiating therapy for urinary tract infections? What is appropriate initial therapy?  Lerner SA


1996 Vol 14 No 4              Clinical approach to community-acquired pneumonia: diagnosis and etiology (Part 2) (Spanish version)  Janoff EN, Rubins JB

                                         Clostridium difficle-associated disease: a persistently plaguing problem.  Gerding DN

1996 Vol 14 No 3              Clinical approach to community-acquired pneumonia: diagnosis and etiology (Part 1)(Spanish version)  Janoff EN, Rubins JB

                                         Multidrug-resistant organisms in cystic fibrosis--an increasingly important problem.  Saiman L

                                         Ask the expert: Is antiviral chemotherapy indicated for people with recurrent cold sores?  Spruance SL

1996 Vol 14 No 2              Management of acute otitis media in an era of changing antimicrobial drug susceptibility …(Russian translation, see page 4)  Klein JO

1996 Vol 14 No 1               Azole antifungal resistance in Candida albicans.  Hitchcock CA

                                         Management of acute community-acquired rhinosinusitis.  Gwaltney JM

                                         Ask the expert: Is penicillin still the antibiotic of choice for streptococcal pharyngitis?  Pichichero ME


1995 Vol 13 No 4               WHONET: a program to monitor local and global spread of resistance.  O'Brien TF, Stelling JM

                                          Treatment of infectious diarrhea: The role of antimicrobial therapy.  Bennish M

                                          Ask the expert: My patients who travel to Mexico or Africa often ask whether they should take antibiotics to prevent traveler's diarrhea. What should I                                               advise them?  Gorbach S

1995 Vol 13 No 3               Integrons: novel mobile genetic elements mediating antibiotic resistance in enterobacteria and Pseudomonas.  Roy PH

                                          Impact of penicillin-resistant pneumococci on clinical practice.  Low DE, de Azavedo J, McGeer A

                                          Ask the expert: Should physicians prescribe antibiotics over the telephone?  Kunin CM

1995 Vol 13 No 2               Acinetobacter baumannii: A newly emerging nosocomial pathogen.  Urban C, Rahal JJ

1995 Vol 13 No 1                Long term surveillance of resistance in Neisseria gonorrhoeae in the Netherlands.  Van Klingeren B, Dessens M, van Santen M


1994 Vol 12 No 4               Antibiotic resistance in Haemophilus influenzae in Portugal.  Lavado B, Pato V

                                          Antimicrobial resistance among enteropathogens in Singapore, 1989-1992.  Tay L, Lim YS, Sng EH

1994 Vol 12 No 3               Antibiotic resistance patterns in bacterial strains isolated in Ethopia.  Mergersa D

                                         New trends in enterobacterial beta-lactamases.  Nordmann P, Naas T, Labia R

1994 Vol 12 No 1               Antibiotic resistance of Shigella isolates during 1990-1992 in Vietnam.  Lien HT et al


1993 Vol 11 No 4                The role of selective antibiotic concentrations on the evolution of antimicrobial resistance.  Baquero B et al